Dr. Andreeva focuses on structural and mechanistic aspects of inflammatory pathways underlying cancer and multiple other pathologies. Inflammation is an early response to various infections and damage initiated by the immune system. While it is essential for pathogen clearance and tissue repair, uncontrolled chronic inflammation promotes cancer development and all stages of tumorigenesis. Since inflammation is one of the hallmarks of cancer, understanding the processes leading to inflammation is critical for development of the next generation of cancer therapeutics. By using various structural, biochemical, and cell-based approaches, Dr. Andreeva aims to explain inflammatory pathways on a molecular level and provide a foundation for novel anti-inflammatory and anti-cancer treatments.