Current and Former Awardees
Clinical Investigators
2024 Recipients
Steven M. Corsello, MD
"Targeting intrinsic immune signaling in pancreatic cancer with small molecule therapeutics"
at
Stanford University School of Medicine
Megan L. Insco, MD, PhD
"Targeting cancer-associated aberrant RNA to treat metastatic melanoma"
at
Dana-Farber Cancer Institute
Mary M. Mullen, MD
"COPS5 as a novel therapeutic target in platinum-resistant ovarian cancer"
at
Erin M. Parry, MD, PhD
"Defining follicular lymphoma transformation: molecular basis, detection and therapeutic vulnerabilities"
at
Dana-Farber Cancer Institute
John R. Prensner, MD, PhD
"Therapeutic opportunities and biological mechanisms for protein-RNA dyssynchrony in medulloblastoma"
at
University of Michigan, Ann Arbor
Lachelle D. Weeks, MD, PhD
"Predicting leukemia risk from peripheral blood smears"
at
Dana-Farber Cancer Institute
2023 Recipients
Sylvan C. Baca, MD, PhD
"Epigenetic drivers of resistance to novel therapies for bladder and kidney cancer"
at
Dana-Farber Cancer Institute
Pavan Bachireddy, MD
"Immune evasive circuits that define MRD progression in myelodysplastic syndrome"
at
The University of Texas MD Anderson Cancer Center
Andrew L. Ji, MD
"Dissecting spatial crosstalk in squamous cell carcinoma arising in organ transplant recipients"
at
Icahn School of Medicine at Mount Sinai
Benjamin A. Nacev, MD, PhD
"Understanding and targeting chromatin reorganization in ATRX deficient sarcomas"
at
University of Pittsburgh
Fyza Y. Shaikh, MD, PhD
"Defining microbiome stability and longitudinal shifts as biomarkers of tumor response to immune checkpoint inhibitors across multiple malignancies"
at
The Johns Hopkins University School of Medicine
Santosha A. Vardhana, MD, PhD
"Overcoming metabolic suppression of anti-tumor immunity in gastric cancer"
at
Memorial Sloan Kettering Cancer Center
2022 Recipients
Daniel J. Delitto, MD, PhD
"Pathogen sensing in fibroblasts restrains antitumor immunity in pancreatic cancer"
at
Stanford University
Xiuning Le, MD, PhD
"Structure- and lineage-based classification and targeting of resistance in EGFR-mutant NSCLC"
at
The University of Texas MD Anderson Cancer Center
Nathan Singh, MD
"Tailored cellular engineering to overcome costimulation-driven CAR T cell dysfunction"
at
Washington University
Melody Smith, MD
"Regulatory mechanisms of the intestinal microbiome on chimeric antigen receptor T cells"
at
Stanford University
Aaron D. Viny, MD
"Epigenetic coupling of DNA methylation and chromatin structure on leukemic transformation and therapeutic response"
at
Columbia University
2021 Recipients
Kelly L. Bolton, MD, PhD
"The use of ivosidenib in IDH1-mutated clonal cytopenia of undetermined significance"
at
Washington University School of Medicine
Alexander C. Huang, MD
"Shared antigen and neoantigen-specific T cells in checkpoint blockade efficacy and toxicity"
at
University of Pennsylvania
David Y. Oh, MD, PhD
"Co-receptors modulating anti-tumor activity of human cytotoxic CD4+ effector cells"
at
University of California, San Francisco
Phillip L. Palmbos, MD, PhD
"Targeting TRIM29 to reverse immune checkpoint inhibitor resistance in bladder cancer"
at
University of Michigan
Sangeetha M. Reddy, MD
"Multi-modality approach to enhancing antigen presentation in breast cancers"
at
University of Texas Southwestern Medical Center
Daniel R. Wahl, MD, PhD
"Targeting metabolic interactions in the glioblastoma microenvironment to overcome therapy resistance"
at
University of Michigan
2020 Recipients
Todd A. Aguilera, MD, PhD
"Immunologic responses to short course radiotherapy in rectal adenocarcinoma and the impact of CD40 agonist immunotherapy"
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University of Texas Southwestern Medical Center
Anusha Kalbasi, MD
"IL13Ra2 Chimeric Antigen Receptor (CAR) T cells for metastatic melanoma"
at
Stanford University School of Medicine
Birgit Knoechel, MD, PhD
"Mechanisms of CD8+ T-cell dysfunction and its therapeutic targeting in T-ALL"
at
Dana-Farber Cancer Institute
Yvonne M. Mowery, MD, PhD
"Evaluating and targeting pathways of treatment resistance in head and neck squamous cell carcinoma"
at
University of Pittsburgh
2019 Recipients
Karuna Ganesh, MD, PhD
"Leveraging patient-derived organoid models to define the molecular determinants of metastatic regeneration"
at
Memorial Sloan Kettering Cancer Center
Jennifer M. Kalish, MD, PhD
"Epigenetic and genetic mechanisms of cancer in Beckwith-Wiedemann Syndrome"
at
Children's Hospital of Philadelphia
David G. McFadden, MD, PhD
"Identifying metabolic vulnerabilities in Hürthle cell carcinoma"
at
University of Texas Southwestern Medical Center
Matthew G. Oser, MD, PhD
"Dissecting and therapeutically exploiting synthetic lethality between NOTCH and TRIM28 to drive anti-tumor immunity in SCLC"
at
Dana-Farber Cancer Institute
Kavita Y. Sarin, MD, PhD
"Genetic contributions and novel therapies for individuals with frequent basal cell cancer"
at
Stanford University
2018 Recipients
Collin M. Blakely, MD, PhD
"Mechanisms of incomplete response and primary resistance to the 3rd generation EGFR inhibitor osimertinib in lung cancer"
at
University of California, San Francisco
Brian C. Capell, MD, PhD
"Defining the role of epigenetic enhancer dysfunction in epithelial carcinogenesis"
at
University of Pennsylvania, Philadelphia
Andrew M. Intlekofer, MD, PhD
"Metabolic coupling of the hypoxic niche to stemness"
at
Memorial Sloan Kettering Cancer Center
Christopher A. Klebanoff, MD
"Clinical development of next-generation T cell receptor (TCR)-based adoptive immunotherapies for the treatment of patients with common epithelial malignancies"
at
Memorial Sloan Kettering Cancer Center
Catherine C. Smith, MD
"RNA Polymerase II as therapeutic target in AML with RAS activation"
at
University of California, San Francisco
2017 Recipients
Vinod P. Balachandran, MD
"Recombinant interleukin-33 immunotherapy for pancreatic cancer"
at
Memorial Sloan Kettering Cancer Center
Gavin P. Dunn, MD, PhD
"Characterizing the immunogenic landscapes of malignant brain tumors"
at
Washington University
Piro Lito, MD, PhD
"Modeling responses to targeted ERK signaling inhibition at the single-cell level"
at
Memorial Sloan Kettering Cancer Center
2016 Recipients
Vivek K. Arora, MD, PhD
"Defining a targetable oncogenic dyad in bladder cancer"
at
Washington University
Christopher E. Barbieri, MD, PhD
"Subtype-specific modes of clinical and molecular progression in prostate cancer"
at
Weill Cornell Medicine
Jaehyuk Choi, MD, PhD
"Development of novel therapeutic strategies for aggressive CTCL subtypes"
at
Northwestern University
Heather L. Yeo, MD
"Use of mobile applications to evaluate post surgical recovery in aging patients with GI cancer"
at
Weill Cornell Medicine
2014 Recipients
Stephen T. Oh, MD, PhD
"Leveraging NFkB pathway dysregulation for therapeutic benefit in myeloproliferative neoplasms"
at
Washington University
2013 Recipients
Omar Abdel-Wahab, MD
"Understanding and targeting altered histone modifiers in the myeloid malignancies"
at
Memorial Sloan Kettering Cancer Center
Himisha Beltran, MD
"Utilizing genome sequencing to elucidate mechanisms of resistance in advanced prostate cancer"
at
Weill Medical College of Cornell University
Ann Mullally, MD
"Determining the role of aberrant growth factor signaling in maintaining disease-propagating cells and mediating JAK2 inhibitor resistance in myeloproliferative neoplasms"
at
Brigham and Women's Hospital
Deepak Nijhawan, MD, PhD
"Using chemistry to identify new targets in lung cancer"
at
University of Texas Southwestern Medical Center
Cameron J. Turtle, MD, PhD
"The impact of the colonic microbiota on reconstitution of CD161hi cells and clinical outcomes after allogeneic hematopoietic stem cell transplantation"
at
Fred Hutchinson Cancer Research Center
2011 Recipients
Marie Bleakley, MD, PhD
"Segregating the GVL effect from GVHD in humans"
at
Fred Hutchinson Cancer Research Center
Zsofia K. Stadler, MD
"Genomic assessment of de novo germline cancer susceptibility in pediatric malignancies"
at
Memorial Sloan Kettering Cancer Center
Jean Y. Tang, MD, PhD
"Mechanisms of acquired resistance to Hedgehog pathway inhibitors in basal cell carcinomas"
at
Stanford University
