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Current and Former Awardees

Innovators

2024 Recipients

Daniel J. Puleston, PhD
"A new platform to study cancer biology and therapy in humans" at Icahn School of Medicine at Mount Sinai

2023 Recipients

Lucas Farnung, PhD
"Understanding the mechanistic basis of gene expression regulation by MLL complexes in cancers" at Harvard Medical School
Ryan A. Flynn, MD, PhD
"Tools to target novel cell surface ligands in cancer" at Boston Children's Hospital
Max Jan, MD, PhD
"Programming next-generation NK cell therapies using targeted protein degradation" at Massachusetts General Hospital
(Kathy) Fange Liu, PhD
"Y chromosome proteins in sex bias of cancers in non-reproductive organs" at University of Pennsylvania
Elvin Wagenblast, PhD
"Untangling the evolutionary dependency of childhood leukemia" at Icahn School of Medicine at Mount Sinai

2022 Recipients

Chengcheng Jin, PhD
"Investigating neuro-immune interaction in lung cancer" at University of Pennsylvania
Nora Kory, PhD
"Targeting mitochondrial transporters in cancer" at Harvard T.H. Chan School of Public Health
Jamie B. Spangler, PhD
"Engineered multispecific antibody-drug conjugates as novel cancer immunotherapeutics" at Johns Hopkins University
Santosha A. Vardhana, MD, PhD
"Investigating and targeting T cell exhaustion in solid tumors" at Memorial Sloan Kettering Cancer Center
Ekaterina V. Vinogradova, PhD
"Investigating and targeting T cell exhaustion in solid tumors" at The Rockefeller University
Srinivas R. Viswanathan, MD, PhD
"X marks the spot: exploring how X-chromosome alterations drive sex differences in cancer" at Dana-Farber Cancer Institute

2021 Recipients

Luisa F. Escobar-Hoyos, PhD
"Understanding RNA splicing in tumor-cell adaptation and anti-tumor immunity" at Yale University School of Medicine
Danielle Grotjahn, PhD
"Uncovering structural mechanisms of mitochondrial fragmentation in cancer by cellular cryo-electron tomography" at The Scripps Research Institute
Mandar D. Muzumdar, MD
"Targeting endocrine-exocrine signaling in pancreatic ductal adenocarcinoma progression" at Yale University School of Medicine
Sabrina L. Spencer, PhD
"Causes and consequences of rapid cancer cell adaptation to MAPK pathway inhibitors" at University of Colorado Boulder
Joshua A. Weinstein, PhD
"A novel DNA microscopy platform for rapid discovery of immunogenic tumor neoantigens" at The University of Chicago

2020 Recipients

Liron Bar-Peled, PhD
"Identification of redox vulnerabilities in genetically defined cancers" at Massachusetts General Hospital
Michael E. Birnbaum, PhD
"Decoding and reprogramming tumor-infiltrating T cells by pMHC-targeted lentiviruses" at Massachusetts Institute of Technology
Gregory S. Ducker, PhD
"Targeting phosphatidylcholine metabolism in liver cancer using zebrafish" at Huntsman Cancer Institute at the University of Utah
Kimberley J. Evason, MD, PhD
"Targeting phosphatidylcholine metabolism in liver cancer using zebrafish" at Huntsman Cancer Institute at the University of Utah
Brian B. Liau, PhD
"Investigating allosteric mechanisms regulating DNA methyltransferase enzymes" at Harvard University
Michael E. Pacold, MD, PhD
"Tracing molecular oxygen in pancreatic cancer" at New York University Langone Health
Elli Papaemmanuil, PhD
"Leveraging multi-modal genome profiling approaches to study disease initiation, progression, and response to therapy in TP53 mutated myeloid neoplasms" at Memorial Sloan Kettering Cancer Center

2019 Recipients

Xiaochun Li, PhD
“Investigation of Hedgehog and Wnt signaling mechanisms” at University of Texas Southwestern Medical Center
Jan P. Schuemann, PhD
“Using extreme dose rates to protect healthy tissue in proton radiation therapy” at Massachusetts General Hospital
Alexandra-Chloé Villani, PhD
"Deciphering the Achilles' heel of cancer immunotherapy" at Massachusetts General Hospital

2018 Recipients

Lawrence A. David, PhD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes" at Duke University
Eric S. Fischer, PhD
"Novel mechanisms for small molecule induced targeted degradation of RRM family proteins" at Dana-Farber Cancer Institute
Arnold S. Han, MD, PhD
"Precision T cell receptor-based cancer therapies" at Columbia University
Amaia Lujambio, PhD
"Overcoming resistance to anti-PD1 immunotherapy in hepatocellular carcinoma" at Icahn School of Medicine at Mount Sinai
Wayne O. Miles, PhD
"Maximizing pro-apoptotic protein levels" at The Ohio State University
Anthony D. Sung, MD
"Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes" at Duke University

2017 Recipients

Benjamin L. Martin, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis" at Stony Brook University
David Q. Matus, PhD
"Cell cycle regulation of cellular behaviors associated with cancer metastasis" at Stony Brook University

2016 Recipients

Jason M. Crawford, PhD
"Elucidating the bacterial determinants of colorectal cancer" at Yale University
Piero D. Dalerba, MD
"Using 'single-cell genomics' to resolve the molecular identity of 'cancer stem cells,' and guide their pharmacological eradication" at Columbia University

2015 Recipients

Nicholas T. Ingolia, PhD
"Cis-regulatory code for the translational control of gene expression" at University of California, Berkeley
Christopher M. Jewell, PhD
"Harnessing intra-lymph node controlled release to study and enhance tumor immunity" at University of Maryland
Guillem Pratx, PhD
"Adding a new dimension to flow cytometry: radionuclide-activated cell sorting" at Stanford University
Brian H. Shirts, MD, PhD
"Participatory genetics for defining genotype-phenotype associations of rare cancer variants" at University of Washington
Elçin Ünal, PhD
"Reducing cancer susceptibility by attenuating cellular aging" at University of California, Berkeley

2014 Recipients

Arvin C. Dar, PhD
"Targeting allosteric control in the Ras-MAPK pathway for cancer therapy" at Icahn School of Medicine at Mount Sinai