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James Osei-Owusu, PhD

James Osei-Owusu, PhD

Project title
"Structure and inhibition of the relaxin receptor RXFP1"

The relaxin-2 receptor (RXFP1), which binds a hormone aptly known as relaxin, plays a key role in reproductive and cardiovascular physiology by increasing blood flow and facilitating childbirth. Abnormal signaling of the receptor leads to a variety of cancers, particularly tumors of reproductive tissues. James aims to establish a comprehensive understanding of RXFP1 molecular signaling and how it can be inhibited for cancer treatment. This study will facilitate the discovery of candidate therapeutic agents as well as aid the rational design of drugs for reproductive cancer treatment. Dr. Osei-Owusu received his PhD from Johns Hopkins University, Baltimore and his MSc and BSc from the University of Ghana, Legon.

 

Research area
Sponsor(s) / Mentor(s)
Andrew C. Kruse, PhD