David E. Lebwohl, MD (Damon Runyon Fellow ‘86-‘87) of Novartis, East Hanover, and colleagues, reported results of a Phase III clinical trial testing the treatment combination of everolimus (Afinitor), which blocks a protein known to affect blood vessel growth in cancer cells, and the hormone therapy exemestane (Aromasin). 724 metastatic breast cancer patients with hormone receptor-positive tumors were enrolled in the trial. Patients who received the combination survived progression-free for twice as long as those who only received exemestane (7.4 months vs. 3.2 months). The study was published in the New England Journal of Medicine.